The cathedral was built from 1758 to1762 in baroque style. Two higher steeples and one smaller between them are prominent features at the front. There are stained glass windows, the work of German and Czech masters, and above the choir apse there is a large stained glass of St. Nicholas.
There is a huge iconostasis in the altar space painted by Teodor Kračun and Jakov Orfelin. In the right angle of the iconostasis there is the throne icon representing the Virgin Mary with the infant Jesus, the work of the unknown Russian painters from the 14th century. There is also a red coffin in the altar space containing the holy relics of St. Arsenije. During Patriarch Georgije Branković, the famous Serbian artist Paja Jovanović painted a few paintings with motives from the Old and the New Testament, as well as four compositions with events from medieval Serbian history.
The facade of the cathedral was redone in 1909/10, during Patriarch Lukijan Bogdanović and according to the project of Vladimir Nikolić.